Research shows that wearing your mask, and opening the front passenger window, and the window behind the driver seat helps to reduce the spread of the novel coronavirus in your vehicle. See this NY Times article.
I travel to the Sacramento nearly every weekend. Usually leave Fresno by 6:30PM Friday to arrive in Sac area by 9PM. Return to Fresno by 8PM Sunday (leave Sac by 5:30PM). Reach out to me if you are interested in carpooling as a driver or passenger.